Type of publication: | Artikel |
Zeitschrift: | Neuroscience |
Band: | 300 |
Jahr: | 2015 |
Seiten: | 425 - 431 |
Notiz: | "" |
ISSN: | 0306-4522 |
URL: | http://www.sciencedirect.com/s... |
DOI: | 10.1016/j.neuroscience.2015.05.058 |
Abriss: | Convergent evidence suggests that the lateral frontal cortex is at the heart of a brain network subserving cognitive control. Recent theories assume a functional segregation along the rostro-caudal axis of the lateral frontal cortex based on differences in the degree of complexity of cognitive control. However, the functional contribution of specific rostral and caudal sub-regions remains elusive. Here we investigate the impact of disrupting rostral and caudal target regions on cognitive control processes, using Transcranial Magnetic Stimulation (TMS). Participants performed three different task-switching conditions that assessed differences in the degree of complexity of cognitive control processes, after temporally disrupting rostral, or caudal target regions, or a control region. Disrupting the rostral lateral frontal region specifically impaired behavioral performance of the most complex task-switching condition, in comparison to the caudal target region and the control region. These novel findings shed light on the neuroanatomical architecture supporting control over goal-directed behavior. |
Schlagworte: | lateral frontal cortex |
Autoren: | |
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