Publikationen

Type of publication:	Artikel
Zeitschrift:	Neuroscience
Band:	300
Jahr:	2015
Seiten:	425 - 431
Notiz:	""
ISSN:	0306-4522
URL:	http://www.sciencedirect.com/s...
DOI:	10.1016/j.neuroscience.2015.05.058
Abriss:	Convergent evidence suggests that the lateral frontal cortex is at the heart of a brain network subserving cognitive control. Recent theories assume a functional segregation along the rostro-caudal axis of the lateral frontal cortex based on differences in the degree of complexity of cognitive control. However, the functional contribution of specific rostral and caudal sub-regions remains elusive. Here we investigate the impact of disrupting rostral and caudal target regions on cognitive control processes, using Transcranial Magnetic Stimulation (TMS). Participants performed three different task-switching conditions that assessed differences in the degree of complexity of cognitive control processes, after temporally disrupting rostral, or caudal target regions, or a control region. Disrupting the rostral lateral frontal region specifically impaired behavioral performance of the most complex task-switching condition, in comparison to the caudal target region and the control region. These novel findings shed light on the neuroanatomical architecture supporting control over goal-directed behavior.
Schlagworte:	lateral frontal cortex
Autoren:	Bahlmann, J. Beckmann, I. Kuhlemann, Ivo Schweikard, Achim Münte, T. F.
Anhänge

[Bib\|RIS]