Modellierung von Gewebebewegungen und Blutfluss für die klappenerhaltende Rekonstruktion der Aortenwurzel

Project Description

Simulated Aortic Valve

One possible reason for aortic valve insufficiency is the dilatation of the aortic root. In this case, the aortic root is enlarged but the leaflet shape remains unchanged. This dilatation causes the valve diameter to increase so that the leaflets cannot adjoin each other anymore. Hence, the change of the valve geometry induces an insufficiency. For patients with such a diagnosis, aortic valve reconstruction presents an alternative to valve replacement. The shape of the dilated root is remodeled by attaching the patient's native leaflets to a prosthesis.

In this project we develop models of the aortic root based on patient-specific geometric features taken from transesophageal (TEE) ultrasound images of the heart. Furthermore, these model will be incorporated into an interactive planning tool, which will allow the surgeon to find the optimal prosthesis for the patient at hand.

Figure (1) Schematic depiction of the construction of a patient-specific aortic valve model, (2) Silicon cast and CT reconstruction of an aortic root and resulting models (3) Geometric parameters from a TEE image of the aortic root and resulting model of the aortic valve.

Publications

Contact Person

Jannis Hagenah
Bldg 64 / Room 89 +49 451 31015215


Former project members
  • Birgit Stender
  • Hamid Hadjar

2014

Jannis Hagenah, Michael Scharfschwerdt, Christoph Metzner, Alexander Schlaefer, HH Sievers and Achim Schweikard, An approach for patient specific modeling of the aortic valve leaflets, in: BioMedTec Studierendentagung, 2014
[Bib|RIS]
Jannis Hagenah, Michael Scharfschwerdt, Christoph Metzner, Alexander Schlaefer, HH Sievers and Achim Schweikard, An approach for patient specific modeling of the aortic valve leaflets, GRIN Verlag, 2014
[Bib|RIS]
Oliver Blanck, Svenja Ipsen, Brad Oborn, Ralf Bruder, René Werner, F. Bode, P. Hunold, Gary Liney, Dirk Rades, Jürgen Dunst, Achim Schweikard and Paul J. Keall, Treatment planning for cardiac radiosurgery – initial human simulations, in: Joint Conference of the SGSMP, DGMP and ÖGMP, Swiss, German and Austrian Society of Medical Physics (SSRMP, DGMP, ÖGMP), Zürich, Switzerland, 2014
[Bib|RIS]

2013

Jannis Hagenah, Michael Scharfschwerdt, Birgit Stender, Sven Ott, R Friedl, HH Sievers and Alexander Schlaefer, A setup for ultrasound based assessment of the aortic root geometry, 2013
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[Bib|RIS]
Bo Wang, Birgit Stender, T Long, Z Zhang and Alexander Schlaefer, An approach to validate ultrasound surface segmentation of the heart, 2013
[Bib|RIS]
Jannis Hagenah, Erstellung eines patientenindividuellen Modells der Aortenklappe, Universität zu Lübeck, 2013
[Bib|RIS]
Birgit Stender, Floris Ernst, Bo Wang, Z. X. Zhang and Alexander Schlaefer, Motion compensation of optical mapping signals from isolated beating rat hearts, in: Applications of Digital Image Processing XXXVI, SPIE, San Diego, CA, pages 88561C-1 - 88561C-6, SPIE, 2013
[DOI]
[Bib|RIS]

2012

2011

Birgit Stender, Michael Scharfschwerdt, Floris Ernst, Ralf Bruder, Hamid Hadjar and Alexander Schlaefer, Optical Imaging of Cardiac Function: System setup and calibration, in: Proceedings of the 25th International Congress and Exhibition on Computer Assisted Radiology and Surgery ({CARS}'11), Berlin, Germany, pages S42-S43, 2011
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[Bib|RIS]