Treatment Planning in Radiosurgery

Project Description

The term radiosurgery refers to very focussed delivery of ionizing radiation in order to treat a target region while sparing surrounding tissue. With the robotic CyberKnife system (Accuray Inc.) a large number of non-coplanar, non-isocentric beams can be generated. While the systems allows for excellent conformality and flexible treatments, the planning problem is challenging. We study various methods to further improve treatment plan optimization.

Interactive treatment planning for radiosurgery

We investigate treatment planning methods, in which the human planner actively interacts with a virtual three-dimensional scene to locally affect the planning outcome, by manipulating the isodose surfaces.

Efficient Optimization for Robotic Radiosurgery

Robotic radiosurgery is characterized by a large number of beams delivered by a robot mounted linear accellerator. While the fexibility in beam delivery allows for very tumor conformal dose distributions it is challenging during treatment planning, where a large optimization problem needs to be solve. We develop efficient beam generation approaches considering the patient geometry and the planning objectives.

4D and 5D planning for radiation therapy

While active beam motion can be used to compensate for the most severe artifacts of organ motion, changes in the target shape or in the motion pattern need to be addressed by adaptive planning methods. 4D planning refers to pre-fraction adaptation to the prevalent motion pattern, and 5D planning to intra-fraction adaptation.


Contact Person

Achim Schweikard
Bldg 64 / Room 97 +49 451 31015200

Floris Ernst
Bldg 64 / Room 95 +49 451 31015208

Former project members
  • Prof. Alexander Schlaefer
  • Tiberiu Viulet


Tiberiu Viulet, Norman Rzezovski and Alexander Schlaefer, Three-Dimensional Isodose Surface Manipulation for Multi-Criteria Inverse Planning in Radiosurgery, 2011
Tiberiu Viulet, Norman Rzezovski and Alexander Schlaefer, Towards interactive planning for radiotherapy by three-dimensional iso-dose manipulation, 2011


Alexander Schlaefer, Oliver Blanck and Achim Schweikard, Interactive Multi-criteria Inverse Planning for Robotic Radiosurgery, in: XVth International Conference on the Use of Computers in Radiation Therapy (ICCR 2007), Toronto, Canada,, 2007
Alexander Schlaefer, O. Jungmann, Warren Kilby and Achim Schweikard, Objective specific beam generation for image guide robotic radiosurgery, in: Computer Assisted Radiology and Surgery (CARS 2007), 2007


Oliver Blanck, Alexander Schlaefer and Achim Schweikard, 3D visualization of radiosurgical treatment plans - experience with Java3D and VTK, in: Computational Modelling of Objects Represented in Images Proceedings of the International Symposium CompIMAGE 2006, pages 101 - 106, Taylor & Francis Group, 2006
Pantaleo Romanelli, Achim Schweikard, Alexander Schlaefer and John R. Adler, Jr., Computer aided robotic radiosurgery (2006), in: Computer Aided Surgery, 11:4(161--174)


Achim Schweikard, Rhea Tombropoulos and John R. Adler, Jr., Robotic Radiosurgery with Beams of Adaptable Shapes, in: Proceedings of the first international conference on Computer Vision, Virtual Reality and Robotics in Medicine ({CVRMed'95}), Nice, France, pages 138--149, Springer, 1995