Type of publication: | Artikel |
Zeitschrift: | Technology in Cancer Research and Treatment |
Band: | 6 |
Nummer: | 4 |
Jahr: | 2007 |
Monat: | August |
Seiten: | 321--328 |
Notiz: | Motion Compensation in Radiosurgery |
ISSN: | 1533-0346 |
Abriss: | To describe the technological background, the accuracy, and clinical feasibility for single session lung radiosurgery using a real-time robotic system with respiratory tracking. The latest version of image-guided real-time respiratory tracking software (Synchrony®, Accuray Incorporated, Sunnyvale, CA) was applied and is described. Accuracy measurements were performed using a newly designed moving phantom model. We treated 15 patients with 19 lung tumors with robotic radiosurgery (CyberKnife®, Accuray) using the same treatment parameters for all patients. Ten patients had primary tumors and five had metastatic tumors. All patients underwent computed tomography-guided percutaneous placement of one fiducial directly into the tumor, and were all treated with single session radiosurgery to a dose of 24 Gy. Follow up CT scanning was performed every two months. All patients could be treated with the automated robotic technique. The respiratory tracking error was less than 1 mm and the overali shape of the dose profile was not affected by target motion and/or phase shift between fiducial and optical marker motion. Two patients required a chest tube insertion after fiducial implantation because of pneumothorax. One patient experienced nausea after treatment. No other short-term adverse reactions were found. One patient showed imaging signs of pneumonitis without a clinical correlation. Single-session radiosurgery for lung tumor tracking using the described technology is a stable, safe, and feasible concept for respiratory tracking of tumors during robotic lung radiosurgery in selected patients. Longer follow-up is needed for definitive clinical results. |
Nutzerfelder: | file={mdws_07.pdf:mdws_07.pdf:PDF} |
Schlagworte: | Cyberknife, Image guided robotics, Lung radiosurgery , Radiosurgery |
Autoren: | |
Anhänge
|
|
[Bib|RIS] | |
|