{T}echnical {D}escription, {P}hantom {A}ccuracy, and {C}linical {F}easibility for {S}ingle-session {L}ung {R}adiosurgery {U}sing {R}obotic {I}mage-guided {R}eal-time {R}espiratory {T}umor {T}racking
| Type of publication: | Artikel |
| Zeitschrift: | Technology in Cancer Research and Treatment |
| Band: | 6 |
| Nummer: | 4 |
| Jahr: | 2007 |
| Monat: | August |
| Seiten: | 321--328 |
| Notiz: | Motion Compensation in Radiosurgery |
| ISSN: | 1533-0346 |
| Abriss: | To describe the technological background, the accuracy, and clinical feasibility for single session lung radiosurgery using a real-time robotic system with respiratory tracking. The latest version of image-guided real-time respiratory tracking software (Synchrony®, Accuray Incorporated, Sunnyvale, CA) was applied and is described. Accuracy measurements were performed using a newly designed moving phantom model. We treated 15 patients with 19 lung tumors with robotic radiosurgery (CyberKnife®, Accuray) using the same treatment parameters for all patients. Ten patients had primary tumors and five had metastatic tumors. All patients underwent computed tomography-guided percutaneous placement of one fiducial directly into the tumor, and were all treated with single session radiosurgery to a dose of 24 Gy. Follow up CT scanning was performed every two months. All patients could be treated with the automated robotic technique. The respiratory tracking error was less than 1 mm and the overali shape of the dose profile was not affected by target motion and/or phase shift between fiducial and optical marker motion. Two patients required a chest tube insertion after fiducial implantation because of pneumothorax. One patient experienced nausea after treatment. No other short-term adverse reactions were found. One patient showed imaging signs of pneumonitis without a clinical correlation. Single-session radiosurgery for lung tumor tracking using the described technology is a stable, safe, and feasible concept for respiratory tracking of tumors during robotic lung radiosurgery in selected patients. Longer follow-up is needed for definitive clinical results. |
| Nutzerfelder: | file={mdws_07.pdf:mdws_07.pdf:PDF} |
| Schlagworte: | Cyberknife, Image guided robotics, Lung radiosurgery , Radiosurgery |
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