{T}echnical {D}escription, {P}hantom {A}ccuracy, and {C}linical {F}easibility for {S}ingle-session {L}ung {R}adiosurgery {U}sing {R}obotic {I}mage-guided {R}eal-time {R}espiratory {T}umor {T}racking

Type of publication:  Artikel
Zeitschrift: Technology in Cancer Research and Treatment
Band: 6
Nummer: 4
Jahr: 2007
Monat: August
Seiten: 321--328
Notiz: Motion Compensation in Radiosurgery
ISSN: 1533-0346
Abriss: To describe the technological background, the accuracy, and clinical feasibility for single session lung radiosurgery using a real-time robotic system with respiratory tracking. The latest version of image-guided real-time respiratory tracking software (Synchrony®, Accuray Incorporated, Sunnyvale, CA) was applied and is described. Accuracy measurements were performed using a newly designed moving phantom model. We treated 15 patients with 19 lung tumors with robotic radiosurgery (CyberKnife®, Accuray) using the same treatment parameters for all patients. Ten patients had primary tumors and five had metastatic tumors. All patients underwent computed tomography-guided percutaneous placement of one fiducial directly into the tumor, and were all treated with single session radiosurgery to a dose of 24 Gy. Follow up CT scanning was performed every two months. All patients could be treated with the automated robotic technique. The respiratory tracking error was less than 1 mm and the overali shape of the dose profile was not affected by target motion and/or phase shift between fiducial and optical marker motion. Two patients required a chest tube insertion after fiducial implantation because of pneumothorax. One patient experienced nausea after treatment. No other short-term adverse reactions were found. One patient showed imaging signs of pneumonitis without a clinical correlation. Single-session radiosurgery for lung tumor tracking using the described technology is a stable, safe, and feasible concept for respiratory tracking of tumors during robotic lung radiosurgery in selected patients. Longer follow-up is needed for definitive clinical results.
Nutzerfelder: file={mdws_07.pdf:mdws_07.pdf:PDF}
Schlagworte: Cyberknife, Image guided robotics, Lung radiosurgery , Radiosurgery
Autoren: Muacevic, Alexander
Drexler, Christian
Wowra, A.
Schweikard, Achim
Schlaefer, Alexander
Hoffmann, R. T.
Wilkowski, R.
Winter, H.